Resveratrol is a polyphenolic compound found in grapes, red wine, purple grape juice, peanuts, and some berries.¹ Some types of plants produce resveratrol and other stilbenes in response to stress, injury, fungal infection, or ultraviolet (UV) radiation.²
Scientists became interested in exploring potential health benefits of resveratrol in 1992 when its presence was first reported in red wine, leading to speculation that resveratrol might help explain the “French Paradox”. Since then, different studies have found resveratrol to be a powerful antioxidant, with anti-aging, anti-fungal, and anti-inflammatory benefits. More recently, reports on the potential for resveratrol to inhibit the development of cancer and extend lifespan in cell culture and animal models have continued to generate scientific interest.”³
Grapes produce different forms of Resveratrol, including cis-resveratrol and trans-resveratrol. Trans-resveratrol is the type most commonly used in scientific research and trials, and EZ MELTS Resveratrol contains the purest form of trans-resveratrol available, at a 99% concentration.
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“Scientists at Harvard Medical School and elsewhere are studying a compound called resveratrol found in grapes, wine and nuts. At high doses, it appears to prolong life spans and improve health in mice… mice who took resveratrol lost weight, increased metabolism and doubled their exercise endurance”.
“(Resveratrol) can mimic many of the effects of calorie restriction... Calorie restriction turns on the survival gene… A hungry life seems to lead to a longer life... Surely, those are strong indications that a restricted calorie intake among humans would be extremely beneficial.”
– 60 minutes (CBS News)
“Oenophiles rejoiced last week when headlines trumpeted a study suggesting that the fountain of youth flows with red wine. Scientists at Harvard Medical School and the National Institute on Aging found that mice fed a high-calorie diet along with large doses of resveratrol—a natural substance found in grape skins—lived longer than mice given no resveratrol. Many of the negative effects of gluttony, such as liver damage and diabetes, were mitigated.”
“Scientists may have found the way to slow (the aging process) down... by using a substance found in red wine that may actually extend life could override an unhealthy lifestyle.”
- NBC Nightly News
“Can you have your cake and eat it? Is there a free lunch after all, red wine included? Researchers at the Harvard Medical School and the National Institute on Aging report that a natural substance found in red wine, known as resveratrol, offsets the bad effects of a high-calorie diet in mice and significantly extends their lifespan.”
“Resveratrol is found in red wines and produced by a variety of plants when put under stress… Since 2003, resveratrol has been shown to extend the lifespan of worms and flies by nearly 30 percent, and fish by almost 60 percent. It has also been shown to protect against Huntington's disease in two different animal models.” 4
"Resveratrol has the ability to prevent the first step that occurs when estrogen starts the process that leads to cancer by blocking the formation of the estrogen DNA adducts. We believe that this could stop the whole progression that leads to breast cancer down the road," said Eleanor G. Rogan, Ph.D., a professor in the Eppley Institute for Research in Cancer and Allied Diseases at the University of Nebraska Medical Center.” 5
“Caloric restriction is highly effective in extending life in many species. .. In this study, the effects of low doses of resveratrol (on genes) were comparable to caloric restriction, the hallmark for life extension.” 6